What role does the ultraviolet sterilization process in pharmaceutical process?

by:Tepro     2020-04-10
Uv disinfection system is an important technology tool, can ensure that pure water loop running under the highest standard of microbial contamination. The benefits are many easy installation, cover an area of an area small, simple maintenance, can be carried out by site personnel. As a kind of chemical processing method, will not affect the stability of the products, and the residue, color and smell of products there will be no accident. Important role in the process of ultraviolet sterilization process in the pharmaceutical uv light sterilizer disinfector is usually divided into two distinct types: low voltage and medium voltage. Uv output monochromatic spectrum (low pressure system 254 nm wavelength) And medium voltage system output multi-color uv spectrum ( Wavelength between 240 & ndash; 310 nm) 。 Ultraviolet (uv) by interrupting microbial DNA ( DNA) Adenine and thiamine molecules, making it cannot continue to breed. Microbes and thus can be used in not under the condition of chemical killed. Despite the 254 nm wavelength is effective disinfection, DNA can most effectively absorption wavelength of 265 nm uv light. Understand the different wavelength uv light sterilizer ability difference is designed has good sterilization effect, high efficiency the foundation of ultraviolet disinfection equipment. Overall, the low pressure system is best for small flow, intermittent, and intermediate pressure technology is more suitable for high velocity water disinfection. Pharmaceutical production is generally consists of several process period, between the different stages may be damaged by microbial contamination, and ultraviolet disinfection can be used as an effective safeguard, to ensure that the drugs in each process section between metamorphic will not occur. Uv installation typical stage is after the activated carbon filter or RO before, or set the uv disinfection and TOC degradation system in fine processing unit. Activated carbon filter followed by ultraviolet disinfection system or RO right before processing unit with a suitable uv disinfection system would kill into the water 99. 9% of the bacteria. After the installation of uv system, not only save the cost, and ultraviolet (uv) provides a high standard of dechlorination effect, and avoid all the chemical substances and the disadvantage of granular activated carbon filter. Ultraviolet ( UV) Initially, technology is used to ensure that urban tap water disinfection. Since it was introduced the technology more than 40 years ago, is now used worldwide, many industries including pharmaceutical companies of disinfection and TOC ( The content of total organic carbon) Degradation, ozone and chloramine decomposition and production technology of residual chlorine removal with water. Water is one of the largest material in the process of drug dosage, the more strict standard driver and the increasingly complex technology request of disinfection technology has been adopted.
Whether it's automation or artificial intelligence, the rapid convergence of technology and business often determines uv light disinfection’s competitiveness.
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